STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpCIndole-3-glycerol phosphate synthase; Identified by similarity to SP:P20577; match to protein family HMM PF00218; Belongs to the TrpC family. (261 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpE
Anthranilate synthase, component I; Identified by similarity to SP:P05378; match to protein family HMM PF00425; match to protein family HMM PF04715.
 
 0.999
trpG
Anthranilate synthase, component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566.
  
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.998
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.998
PRU_1351
Pyridoxal-phosphate dependent TrpB-like protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
 0.930
hisIE
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Identified by similarity to SP:P06989; match to protein family HMM PF01502; match to protein family HMM PF01503; match to protein family HMM TIGR03188; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.675
PRU_1172
Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; Identified by match to protein family HMM PF00793; match to protein family HMM PF01817.
  
  
 0.632
PRU_0721
Shikimate dehydrogenase; Identified by similarity to SP:P54374; match to protein family HMM PF01488; match to protein family HMM PF08501.
 
 
 0.559
hisB
Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Identified by similarity to SP:P06987; match to protein family HMM PF00475; match to protein family HMM TIGR01261; match to protein family HMM TIGR01656; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
     
 0.507
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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