Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PRU_1600Identified by match to protein family HMM PF00135; Belongs to the type-B carboxylesterase/lipase family. (509 aa)    
Predicted Functional Partners:
PRU_1673
Lipase domain protein; Identified by similarity to GB:AAF87662.1.
 
  
 0.575
PRU_1599
Identified by match to protein family HMM PF03372.
       0.559
PRU_2746
Putative xylanase; Identified by similarity to SP:P10478; match to protein family HMM PF00756.
 
     0.442
gmk
Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.434
xyn10D-fae1A
Glycosyl hydrolase, family 10/isoamylase domain/esterase family protein; Involved in degradation of plant cell wall polysaccharides. Has endo-xylanase activity towards substrates such as oat spelt xylan (OSX), acetylated xylo-oligosaccharides and acetylated xylan, producing primarily xylobiose; cannot hydrolyze xylobiose to xylose. Also has feruloyl esterase activity, releasing ferulic acid from methylferulate, and from the more natural substrates wheat bran, corn fiber, and XOS(FA,Ac), a corn fiber-derived substrate enriched in O-acetyl and ferulic acid esters. Exhibits negligible ace [...]
 
     0.402
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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