STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRU_1646Tagaturonate reductase; Identified by similarity to SP:P24214; match to protein family HMM PF01232; match to protein family HMM PF08125. (479 aa)    
Predicted Functional Partners:
uxaA
Altronate dehydratase; Identified by similarity to SP:P42604; match to protein family HMM PF04295; match to protein family HMM PF08666.
 
 0.983
uxaC
Glucuronate isomerase; Identified by match to protein family HMM PF02614.
 
 
 0.960
uvrA_2
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.773
PRU_1648
Conserved hypothetical protein; Identified by similarity to GB:AAO79446.1.
       0.727
PRU_1649
ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.
       0.727
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.654
kduI
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.639
PRU_1650
Conserved hypothetical protein; Identified by similarity to GB:AAO76164.1.
       0.639
PRU_0735
Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.
  
     0.628
PRU_1461
Pectinase family protein/glycosyl hydrolase family 88; Identified by match to protein family HMM PF00295; match to protein family HMM PF07470; Belongs to the glycosyl hydrolase 28 family.
 
  
 0.532
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.