STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
serBPhosphoserine phosphatase SerB; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM PF08282; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (410 aa)    
Predicted Functional Partners:
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.946
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.942
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 
 0.921
PRU_1351
Pyridoxal-phosphate dependent TrpB-like protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.907
PRU_1894
Putative CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to SP:P39823; match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.906
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
 0.905
hisIE
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Identified by similarity to SP:P06989; match to protein family HMM PF01502; match to protein family HMM PF01503; match to protein family HMM TIGR03188; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.858
PRU_1528
Putative serine acetyltransferase; Identified by similarity to PIR:S69192; match to protein family HMM PF00132.
  
 
 0.831
cysE
Serine O-acetyltransferase; Identified by similarity to SP:Q59967; match to protein family HMM PF00132.
  
 
 0.831
PRU_2687
Putative bacterial transferase.
  
 
 0.831
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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