STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRU_2190ATP:cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; Belongs to the Cob(I)alamin adenosyltransferase family. (187 aa)    
Predicted Functional Partners:
cobP
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Identified by similarity to SP:P29931; match to protein family HMM PF02283.
    
 0.921
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
    
 0.919
cobS
Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
 0.919
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
 0.918
cobB
Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379.
    
 0.915
PRU_2189
Conserved hypothetical protein; Identified by similarity to GB:AAM72893.1.
       0.618
cobL
precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by similarity to SP:P21921; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
     
 0.541
cobJH
precorrin-3B C17-methyltransferase/precorrin-8X methylmutase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02570; match to protein family HMM TIGR01466.
     
 0.536
cobM
Cobalamin biosynthesis protein CbiG/precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01465.
     
 0.509
cobKD
Precorrin-6x reductase/cobalamin biosynthetic protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
     
 0.495
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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