Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
nrdG_2Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (165 aa)    
Predicted Functional Partners:
nrdD_2
Anaerobic ribonucleoside-triphosphate reductase; Identified by similarity to SP:P28903; match to protein family HMM PF03477; match to protein family HMM TIGR02487.
 
 
 0.982
queF
GTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.734
PRU_2850
Fe-S metabolism associated family protein; Identified by match to protein family HMM PF02657.
       0.711
nrdD_1
Anaerobic ribonucleoside-triphosphate reductase; Identified by similarity to SP:P28903; match to protein family HMM PF03477; match to protein family HMM TIGR02827.
  
 
 0.683
queC
Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.600
PRU_1536
Radical SAM domain protein; Identified by match to protein family HMM PF04055.
 
   
 0.420
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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