STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Moth_0103Serine phosphatase. (680 aa)    
Predicted Functional Partners:
Moth_0851
Sporulation factor SpoIIGA, Unknown type peptidase, MEROPS family U04; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.960
Moth_0852
RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.892
Moth_0854
Hypothetical protein.
  
   
 0.887
Moth_2372
Transcription regulator of sigma-E/sigma-K-dependent gene spoIIID.
  
   
 0.862
Moth_1319
Stage IV sporulation protein A (spore cortex formation and coat assembly); ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.848
Moth_0083
Transcriptional regulator, AbrB family.
 
   
 0.847
Moth_0578
Hypothetical protein.
  
   
 0.843
Moth_1536
Conserved hypothetical protein.
  
   
 0.839
spoIIAB
Putative anti-sigma regulatory factor (serine/threonine protein kinase); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.825
Moth_0853
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.820
Your Current Organism:
Moorella thermoacetica
NCBI taxonomy Id: 264732
Other names: M. thermoacetica ATCC 39073, Moorella thermoacetica ATCC 39073, Moorella thermoacetica str. ATCC 39073, Moorella thermoacetica strain ATCC 39073
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