STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Moth_1191Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (306 aa)    
Predicted Functional Partners:
Moth_1192
Zinc-finger protein.
 
 0.996
Moth_1198
acetyl-CoA decarbonylase/synthase delta subunit.
  
 0.994
Moth_1197
Dihydropteroate synthase, DHPS.
 
 
 0.984
Moth_1202
acetyl-CoA decarbonylase/synthase beta subunit / acetyl-CoA decarbonylase/synthase alpha subunit.
 
  
 0.982
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.972
Moth_0833
Conserved hypothetical protein.
 
 0.966
Moth_2115
5-methyltetrahydrofolate--homocysteine S-methyltransferase.
 
 
 0.963
Moth_1207
5-methyltetrahydrofolate--homocysteine S-methyltransferase.
 
 
 0.960
Moth_1990
Cystathionine beta-lyase.
  
 0.960
fhs
Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.957
Your Current Organism:
Moorella thermoacetica
NCBI taxonomy Id: 264732
Other names: M. thermoacetica ATCC 39073, Moorella thermoacetica ATCC 39073, Moorella thermoacetica str. ATCC 39073, Moorella thermoacetica strain ATCC 39073
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