node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Moth_1837 | Moth_1839 | Moth_1837 | Moth_1839 | Lytic transglycosylase, catalytic. | Integral membrane protein; Probably functions as a manganese efflux pump. | 0.791 |
Moth_1837 | coaE | Moth_1837 | Moth_1838 | Lytic transglycosylase, catalytic. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.882 |
Moth_1837 | mutM | Moth_1837 | Moth_1840 | Lytic transglycosylase, catalytic. | Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.539 |
Moth_1837 | polA | Moth_1837 | Moth_1841 | Lytic transglycosylase, catalytic. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.689 |
Moth_1839 | Moth_1837 | Moth_1839 | Moth_1837 | Integral membrane protein; Probably functions as a manganese efflux pump. | Lytic transglycosylase, catalytic. | 0.791 |
Moth_1839 | coaE | Moth_1839 | Moth_1838 | Integral membrane protein; Probably functions as a manganese efflux pump. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.921 |
Moth_1839 | mutM | Moth_1839 | Moth_1840 | Integral membrane protein; Probably functions as a manganese efflux pump. | Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.739 |
Moth_1839 | polA | Moth_1839 | Moth_1841 | Integral membrane protein; Probably functions as a manganese efflux pump. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.682 |
Moth_1842 | Moth_1843 | Moth_1842 | Moth_1843 | Hypothetical protein. | RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. | 0.876 |
Moth_1842 | mutM | Moth_1842 | Moth_1840 | Hypothetical protein. | Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.522 |
Moth_1842 | polA | Moth_1842 | Moth_1841 | Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.525 |
Moth_1843 | Moth_1842 | Moth_1843 | Moth_1842 | RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. | Hypothetical protein. | 0.876 |
Moth_1843 | mutM | Moth_1843 | Moth_1840 | RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. | Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.522 |
Moth_1843 | polA | Moth_1843 | Moth_1841 | RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.588 |
coaE | Moth_1837 | Moth_1838 | Moth_1837 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Lytic transglycosylase, catalytic. | 0.882 |
coaE | Moth_1839 | Moth_1838 | Moth_1839 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Integral membrane protein; Probably functions as a manganese efflux pump. | 0.921 |
coaE | guaA | Moth_1838 | Moth_2105 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.431 |
coaE | mutM | Moth_1838 | Moth_1840 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.990 |
coaE | nth | Moth_1838 | Moth_1891 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.522 |
coaE | polA | Moth_1838 | Moth_1841 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.932 |