Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Moth_19852-oxoglutarate ferredoxin oxidoreductase, beta subunit. (281 aa)    
Predicted Functional Partners:
Moth_1984
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
 
 0.993
Moth_0064
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA and carbon dioxide. The two electrons that are generated as a result of pyruvate decarboxylation are used in the reduction of low potential ferredoxins, which provide reducing equivalents for central metabolism. Also catalyzes the reverse reaction, i.e. the synthesis of pyruvate from acetyl-CoA and carbon dioxide. Appears to function physiologically in both directions. The oxidation of pyruvate by PFOR is required to connect glycolysis and the Wood- Ljungdahl pathway of re [...]
  
 0.990
Moth_1986
2-oxoglutarate ferredoxin oxidoreductase, gamma subunit.
 
  0.983
Moth_0033
Pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
 
 0.970
Moth_1593
2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; Catalyzes the anaerobic oxidation of oxalate using a broad range of electron acceptors, including ferredoxin and the nickel- dependent carbon monoxide dehydrogenase. Does not require coenzyme A as cosubstrate. Enables anaerobic growth on oxalate which is used as energy source by the bacteria.
  
 0.967
Moth_0035
2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate.
 
 0.956
Moth_1983
4Fe-4S ferredoxin, iron-sulfur binding protein.
 
  
  0.888
Moth_0378
Pyruvate ferredoxin oxidoreductase, alpha subunit.
 
 0.870
Moth_1922
Pyruvate ferredoxin oxidoreductase, alpha subunit.
 
 0.870
Moth_0376
Pyruvate ferredoxin oxidoreductase, gamma subunit.
 
 0.826
Your Current Organism:
Moorella thermoacetica
NCBI taxonomy Id: 264732
Other names: M. thermoacetica ATCC 39073, Moorella thermoacetica ATCC 39073, Moorella thermoacetica str. ATCC 39073, Moorella thermoacetica strain ATCC 39073
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.