Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Moth_2149Diguanylate cyclase (GGDEF domain). (272 aa)    
Predicted Functional Partners:
Moth_1432
Metal dependent phosphohydrolase.
 
   0.948
Moth_0346
Diguanylate phosphodiesterase (EAL domain).
 
 0.944
Moth_1470
Metal dependent phosphohydrolase.
 
  
 0.870
Moth_2492
Metal dependent phosphohydrolase.
 
   0.861
Moth_0801
MCP methyltransferase, CheR-type.
 
   
  0.856
Moth_0504
Metal dependent phosphohydrolase.
 
   0.855
Moth_1469
Metal dependent phosphohydrolase.
 
   0.841
Moth_2131
Metal dependent phosphohydrolase.
 
   0.827
Moth_2150
Metal dependent phosphohydrolase.
 
 0.787
Moth_2148
Diguanylate cyclase (GGDEF domain) with PAS/PAC sensor.
0.758
Your Current Organism:
Moorella thermoacetica
NCBI taxonomy Id: 264732
Other names: M. thermoacetica ATCC 39073, Moorella thermoacetica ATCC 39073, Moorella thermoacetica str. ATCC 39073, Moorella thermoacetica strain ATCC 39073
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.