STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (198 aa)    
Predicted Functional Partners:
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 0.990
Moth_1819
Molybdopterin guanine dinucleotide biosynthesis accessory protein MobB.
 0.989
Moth_2137
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.886
Moth_2136
Molybdopterin binding domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.883
Moth_1820
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.803
fdhA
Formate dehydrogenase, alpha subunit (F420); Contains selenocysteine; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
     0.791
Moth_0064
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA and carbon dioxide. The two electrons that are generated as a result of pyruvate decarboxylation are used in the reduction of low potential ferredoxins, which provide reducing equivalents for central metabolism. Also catalyzes the reverse reaction, i.e. the synthesis of pyruvate from acetyl-CoA and carbon dioxide. Appears to function physiologically in both directions. The oxidation of pyruvate by PFOR is required to connect glycolysis and the Wood- Ljungdahl pathway of re [...]
  
  
 0.723
Moth_1909
Nitrate reductase (quinol-dependent), catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
     0.721
Moth_0450
Formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.719
Moth_1382
Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.692
Your Current Organism:
Moorella thermoacetica
NCBI taxonomy Id: 264732
Other names: M. thermoacetica ATCC 39073, Moorella thermoacetica ATCC 39073, Moorella thermoacetica str. ATCC 39073, Moorella thermoacetica strain ATCC 39073
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