STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A443HR83Putative phosphatidylinositol 3 and 4-kinase; Belongs to the PI3/PI4-kinase family. (2475 aa)    
Predicted Functional Partners:
A0A443I3H1
3'-5' exonuclease domain-containing protein.
   
 0.999
A0A443HSG1
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
   
0.997
A0A443HXW6
Kinase-like domain-containing protein.
    
 0.987
A0A443I7R1
Nucleotide excision repair factor.
  
 
 0.987
A0A443I390
Protein kinase.
    
 0.986
C8Q69DRAFT_773
Putative cell cycle protein kinase.
    
 0.986
A0A443HJR4
Putative DNA damage repair protein.
    
 0.984
A0A443HPV3
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.983
A0A443HMQ1
Serine/threonine-protein kinase chk2.
    
 0.981
A0A443HIK2
Replication factor-a protein.
   
 0.980
Your Current Organism:
Byssochlamys spectabilis
NCBI taxonomy Id: 264951
Other names: ATCC 90900, B. spectabilis, Byssochlamys spectabilis (Udagawa & Shoji Suzuki) Houbraken & Samson 2008, CBS 101075, FRR 5219, JCM 12815, Pacilomyces variotii, Paecilomyces spectabilis, Paecilomyces variotii, Paecilomyces variotti, Paecilomyces vatiotii, Talaromyces spectabilis
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