node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A443HI65 | A0A443I0S1 | A0A443HI65 | A0A443I0S1 | N-acetyltransferase domain-containing protein. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.807 |
A0A443HI65 | A0A443I1F8 | A0A443HI65 | A0A443I1F8 | N-acetyltransferase domain-containing protein. | O-methyltransferase-domain-containing protein. | 0.807 |
A0A443HI65 | VdtC | A0A443HI65 | A0A443HJY8 | N-acetyltransferase domain-containing protein. | O-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] | 0.807 |
A0A443HK99 | A0A443I0S1 | A0A443HK99 | A0A443I0S1 | Putative GNAT family acetyltransferase. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.675 |
A0A443HK99 | A0A443I1F8 | A0A443HK99 | A0A443I1F8 | Putative GNAT family acetyltransferase. | O-methyltransferase-domain-containing protein. | 0.675 |
A0A443HK99 | VdtC | A0A443HK99 | A0A443HJY8 | Putative GNAT family acetyltransferase. | O-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] | 0.675 |
A0A443HKI6 | A0A443I0S1 | A0A443HKI6 | A0A443I0S1 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.675 |
A0A443HKI6 | A0A443I1F8 | A0A443HKI6 | A0A443I1F8 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | O-methyltransferase-domain-containing protein. | 0.675 |
A0A443HKI6 | VdtC | A0A443HKI6 | A0A443HJY8 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | O-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] | 0.675 |
A0A443HKJ2 | A0A443I0S1 | A0A443HKJ2 | A0A443I0S1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.751 |
A0A443HKJ2 | A0A443I1F8 | A0A443HKJ2 | A0A443I1F8 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | O-methyltransferase-domain-containing protein. | 0.751 |
A0A443HKJ2 | VdtC | A0A443HKJ2 | A0A443HJY8 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | O-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] | 0.751 |
A0A443HLK3 | A0A443I0S1 | A0A443HLK3 | A0A443I0S1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.751 |
A0A443HLK3 | A0A443I1F8 | A0A443HLK3 | A0A443I1F8 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | O-methyltransferase-domain-containing protein. | 0.751 |
A0A443HLK3 | VdtC | A0A443HLK3 | A0A443HJY8 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | O-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] | 0.751 |
A0A443HRZ3 | A0A443I0S1 | A0A443HRZ3 | A0A443I0S1 | Putative GNAT family acetyltransferase. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.675 |
A0A443HRZ3 | A0A443I1F8 | A0A443HRZ3 | A0A443I1F8 | Putative GNAT family acetyltransferase. | O-methyltransferase-domain-containing protein. | 0.675 |
A0A443HRZ3 | VdtC | A0A443HRZ3 | A0A443HJY8 | Putative GNAT family acetyltransferase. | O-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] | 0.675 |
A0A443HYT9 | A0A443I0S1 | A0A443HYT9 | A0A443I0S1 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | S-adenosyl-L-methionine-dependent methyltransferase. | 0.675 |
A0A443HYT9 | A0A443I1F8 | A0A443HYT9 | A0A443I1F8 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | O-methyltransferase-domain-containing protein. | 0.675 |