node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mfla_0058 | argC | Mfla_0058 | Mfla_0057 | Hypothetical protein. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.806 |
argA | argB | Mfla_2252 | Mfla_2255 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.993 |
argA | argC | Mfla_2252 | Mfla_0057 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.995 |
argA | argD | Mfla_2252 | Mfla_1710 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: tbd:Tbd_1851 acetylornithine and succinylornithine aminotransferase; COGs: COG4992 Ornithine/acetylornithine aminotransferase category=E; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.968 |
argA | argF | Mfla_2252 | Mfla_1709 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.969 |
argA | argG | Mfla_2252 | Mfla_1708 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | PRIAM: Argininosuccinate synthase; PFAM: argininosuccinate synthase; ExsB family protein; KEGG: eba:ebA5097 argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase category=E; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.995 |
argA | argH | Mfla_2252 | Mfla_0038 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: tbd:Tbd_0229 argininosuccinate lyase; COGs: COG0165 Argininosuccinate lyase category=E. | 0.988 |
argA | argJ | Mfla_2252 | Mfla_2232 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argA | carB | Mfla_2252 | Mfla_0779 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: tbd:Tbd_1128 carbamoyl-phosphate synthase, large subunit, glutamine-dependent; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) category=F; Belongs to the CarB family. | 0.769 |
argA | glgC | Mfla_2252 | Mfla_1368 | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.716 |
argB | argA | Mfla_2255 | Mfla_2252 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetylglutamate synthase / N-acetylglutamate kinase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; helix-turn-helix domain protein; KEGG: tbd:Tbd_0154 amino-acid N-acetyltransferase (ArgA); COGs: COG0548 Acetylglutamate kinase category=E; Belongs to the acetyltransferase family. ArgA subfamily. | 0.993 |
argB | argC | Mfla_2255 | Mfla_0057 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
argB | argD | Mfla_2255 | Mfla_1710 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: tbd:Tbd_1851 acetylornithine and succinylornithine aminotransferase; COGs: COG4992 Ornithine/acetylornithine aminotransferase category=E; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.993 |
argB | argF | Mfla_2255 | Mfla_1709 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.927 |
argB | argG | Mfla_2255 | Mfla_1708 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PRIAM: Argininosuccinate synthase; PFAM: argininosuccinate synthase; ExsB family protein; KEGG: eba:ebA5097 argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase category=E; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.977 |
argB | argH | Mfla_2255 | Mfla_0038 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: tbd:Tbd_0229 argininosuccinate lyase; COGs: COG0165 Argininosuccinate lyase category=E. | 0.979 |
argB | argJ | Mfla_2255 | Mfla_2232 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argB | carB | Mfla_2255 | Mfla_0779 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: tbd:Tbd_1128 carbamoyl-phosphate synthase, large subunit, glutamine-dependent; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) category=F; Belongs to the CarB family. | 0.616 |
argB | glgC | Mfla_2255 | Mfla_1368 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.676 |
argC | Mfla_0058 | Mfla_0057 | Mfla_0058 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Hypothetical protein. | 0.806 |