STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfla_0385Diguanylate phosphodiesterase (EAL domain). (261 aa)    
Predicted Functional Partners:
Mfla_2656
Multi-sensor hybrid histidine kinase.
  
  
 0.746
Mfla_2587
Multi-sensor hybrid histidine kinase.
  
  
 0.737
Mfla_2628
Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC and GAF sensor(s).
 
 
 0.696
Mfla_0350
Helix-turn-helix, Fis-type; Belongs to the transcriptional regulatory Fis family.
    
 
 0.672
Mfla_1498
Type IV pilus assembly PilZ.
    
   0.635
flhD
Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
    
 
 0.635
Mfla_0665
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s).
  
 
 0.614
Mfla_2288
Diguanylate phosphodiesterase (EAL domain).
  
     0.564
Mfla_1183
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).
 
 
0.502
Mfla_0612
Diguanylate phosphodiesterase (EAL domain).
  
    0.497
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus KT, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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