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Mfla_0748 protein (Methylobacillus flagellatus) - STRING interaction network
"Mfla_0748" - 2-isopropylmalate synthase in Methylobacillus flagellatus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Mfla_07482-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (562 aa)    
Predicted Functional Partners:
leuC
Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (468 aa)
 
  0.994
leuD
Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (214 aa)
 
 
  0.983
ilvD
Dihydroxy-acid dehydratase (616 aa)
   
 
  0.971
Mfla_0626
Branched-chain amino acid aminotransferase (306 aa)
   
  0.964
Mfla_2119
Acetolactate synthase, large subunit (568 aa)
 
 
  0.950
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (351 aa)
 
 
  0.948
Mfla_2734
Glutamate synthase (NADPH) (1836 aa)
   
   
  0.938
Mfla_2120
Acetolactate synthase 3 regulatory subunit (163 aa)
 
 
  0.922
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (654 aa)
   
 
  0.919
Mfla_2075
Dehydrogenase catalytic domain-containing protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (442 aa)
     
  0.911
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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