node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mfla_1652 | Mfla_1656 | Mfla_1652 | Mfla_1656 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | 0.821 |
Mfla_1652 | Mfla_1657 | Mfla_1652 | Mfla_1657 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; ATP-grasp domain protein; KEGG: mca:MCA2864 ribosomal protein S6 modification protein, putative; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) category=J; Belongs to the RimK family. | 0.809 |
Mfla_1652 | Mfla_1659 | Mfla_1652 | Mfla_1659 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | PFAM: protein of unknown function DUF201; KEGG: mca:MCA2862 hypothetical protein; COGs: COG2232 ATP-dependent carboligase related to biotin carboxylase category=R. | 0.818 |
Mfla_1652 | Mfla_1660 | Mfla_1652 | Mfla_1660 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | KEGG: mca:MCA3019 methylene tetrahydromethanopterin dehydrogenase/methylenetetrahydrofolate dehydrogenase, putative; COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase category=I. | 0.989 |
Mfla_1652 | Mfla_1661 | Mfla_1652 | Mfla_1661 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; KEGG: mca:MCA2861 kinase, GHMP family, putative; COGs: COG1907 archaeal sugar kinases category=R. | 0.815 |
Mfla_1652 | Mfla_1662 | Mfla_1652 | Mfla_1662 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | Formylmethanofuran dehydrogenase, subunit B; KEGG: noc:Noc_0025 formylmethanofuran dehydrogenase; COGs: COG1029 Formylmethanofuran dehydrogenase subunit B category=C. | 0.802 |
Mfla_1652 | Mfla_1663 | Mfla_1652 | Mfla_1663 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | PFAM: Amidohydrolase 3; KEGG: mca:MCA2859 formylmethanofurane dehydrogenase, A subunit, putative; COGs: COG1229 Formylmethanofuran dehydrogenase subunit A category=C. | 0.801 |
Mfla_1652 | Mfla_1665 | Mfla_1652 | Mfla_1665 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | PRIAM: Formylmethanofuran dehydrogenase; PFAM: glutamate synthase, alpha subunit domain protein; KEGG: noc:Noc_0022 formylmethanofuran dehydrogenase; COGs: COG2218 Formylmethanofuran dehydrogenase subunit C category=C. | 0.802 |
Mfla_1652 | ffsA | Mfla_1652 | Mfla_1664 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | Formylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. | 0.979 |
Mfla_1652 | mch | Mfla_1652 | Mfla_1658 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. | 0.892 |
Mfla_1656 | Mfla_1652 | Mfla_1656 | Mfla_1652 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. | 0.821 |
Mfla_1656 | Mfla_1657 | Mfla_1656 | Mfla_1657 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; ATP-grasp domain protein; KEGG: mca:MCA2864 ribosomal protein S6 modification protein, putative; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) category=J; Belongs to the RimK family. | 0.974 |
Mfla_1656 | Mfla_1659 | Mfla_1656 | Mfla_1659 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | PFAM: protein of unknown function DUF201; KEGG: mca:MCA2862 hypothetical protein; COGs: COG2232 ATP-dependent carboligase related to biotin carboxylase category=R. | 0.912 |
Mfla_1656 | Mfla_1660 | Mfla_1656 | Mfla_1660 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | KEGG: mca:MCA3019 methylene tetrahydromethanopterin dehydrogenase/methylenetetrahydrofolate dehydrogenase, putative; COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase category=I. | 0.887 |
Mfla_1656 | Mfla_1661 | Mfla_1656 | Mfla_1661 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; KEGG: mca:MCA2861 kinase, GHMP family, putative; COGs: COG1907 archaeal sugar kinases category=R. | 0.873 |
Mfla_1656 | Mfla_1662 | Mfla_1656 | Mfla_1662 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | Formylmethanofuran dehydrogenase, subunit B; KEGG: noc:Noc_0025 formylmethanofuran dehydrogenase; COGs: COG1029 Formylmethanofuran dehydrogenase subunit B category=C. | 0.840 |
Mfla_1656 | Mfla_1663 | Mfla_1656 | Mfla_1663 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | PFAM: Amidohydrolase 3; KEGG: mca:MCA2859 formylmethanofurane dehydrogenase, A subunit, putative; COGs: COG1229 Formylmethanofuran dehydrogenase subunit A category=C. | 0.839 |
Mfla_1656 | Mfla_1665 | Mfla_1656 | Mfla_1665 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | PRIAM: Formylmethanofuran dehydrogenase; PFAM: glutamate synthase, alpha subunit domain protein; KEGG: noc:Noc_0022 formylmethanofuran dehydrogenase; COGs: COG2218 Formylmethanofuran dehydrogenase subunit C category=C. | 0.838 |
Mfla_1656 | ffsA | Mfla_1656 | Mfla_1664 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | Formylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. | 0.839 |
Mfla_1656 | mch | Mfla_1656 | Mfla_1658 | Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H. | Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. | 0.953 |