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acsA protein (Methylobacillus flagellatus) - STRING interaction network
"acsA" - acetyl-CoA synthetase in Methylobacillus flagellatus
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (654 aa)    
Predicted Functional Partners:
Mfla_1995
Lactaldehyde dehydrogenase (506 aa)
   
  0.957
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (395 aa)
     
 
  0.955
Mfla_2734
Glutamate synthase (NADPH) (1836 aa)
   
   
  0.936
Mfla_0024
Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (449 aa)
   
  0.933
Mfla_0025
Biotin carboxyl carrier protein (151 aa)
   
  0.931
Mfla_1512
Pyruvate carboxylase subunit B (617 aa)
   
  0.925
Mfla_0748
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (562 aa)
   
 
  0.919
Mfla_0517
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (515 aa)
   
 
  0.919
Mfla_0740
Phosphate acetyltransferase (318 aa)
   
 
  0.919
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (289 aa)
       
  0.913
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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