node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mfla_0786 | mraY | Mfla_0786 | Mfla_2272 | Phosphoesterase, PA-phosphatase related protein. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.921 |
Mfla_0786 | uppP | Mfla_0786 | Mfla_2527 | Phosphoesterase, PA-phosphatase related protein. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.929 |
ddl | ftsI | Mfla_2266 | Mfla_2275 | D-alanine--D-alanine ligase; Cell wall formation. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.870 |
ddl | ftsW | Mfla_2266 | Mfla_2270 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.909 |
ddl | mraY | Mfla_2266 | Mfla_2272 | D-alanine--D-alanine ligase; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.941 |
ddl | murC | Mfla_2266 | Mfla_2268 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
ddl | murD | Mfla_2266 | Mfla_2271 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.972 |
ddl | murE | Mfla_2266 | Mfla_2274 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.916 |
ddl | murF | Mfla_2266 | Mfla_2273 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddl | murG | Mfla_2266 | Mfla_2269 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.988 |
ftsI | ddl | Mfla_2275 | Mfla_2266 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | D-alanine--D-alanine ligase; Cell wall formation. | 0.870 |
ftsI | ftsW | Mfla_2275 | Mfla_2270 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.992 |
ftsI | mraY | Mfla_2275 | Mfla_2272 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.991 |
ftsI | murC | Mfla_2275 | Mfla_2268 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.904 |
ftsI | murD | Mfla_2275 | Mfla_2271 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.990 |
ftsI | murE | Mfla_2275 | Mfla_2274 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.990 |
ftsI | murF | Mfla_2275 | Mfla_2273 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.956 |
ftsI | murG | Mfla_2275 | Mfla_2269 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.882 |
ftsW | ddl | Mfla_2270 | Mfla_2266 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.909 |
ftsW | ftsI | Mfla_2270 | Mfla_2275 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.992 |