Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mfla_2575Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (298 aa)    
Predicted Functional Partners:
Mfla_0020
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.633
Mfla_2734
PRIAM: Glutamate synthase (NADPH); PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: atc:AGR_C_235 hypothetical protein; COGs: COG0069 Glutamate synthase domain 2 category=E.
 
   
 0.588
Mfla_1669
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.557
Mfla_2574
Pirin-like protein; Belongs to the pirin family.
   
   0.551
Mfla_2576
Protein of unknown function DUF6, transmembrane.
  
    0.544
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.462
Mfla_2573
Isochorismatase hydrolase.
       0.447
Mfla_2587
Multi-sensor hybrid histidine kinase.
   
  
 0.436
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 
 0.431
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.425
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus KT, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
Server load: low (14%) [HD]