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priA protein (Methylobacillus flagellatus) - STRING interaction network
"priA" - Replication restart DNA helicase PriA in Methylobacillus flagellatus
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA (738 aa)    
Predicted Functional Partners:
Mfla_1330
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins (462 aa)
 
 
  0.828
argS
arginyl-tRNA synthetase (556 aa)
   
   
  0.797
Mfla_2424
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism (167 aa)
       
 
  0.747
Mfla_0358
DNA polymerase I (910 aa)
   
   
  0.742
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3’- to 5’- polarity. Unwinds branched duplex DNA (Y-DNA) (686 aa)
 
   
  0.736
Mfla_2065
Exonuclease RecJ (564 aa)
 
   
  0.735
priB
Single-strand binding protein/primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS) (99 aa)
       
 
  0.699
Mfla_2674
Sporulation related (198 aa)
   
        0.649
Mfla_0002
DNA polymerase III, beta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (367 aa)
   
   
  0.645
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (199 aa)
     
 
  0.638
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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