STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiItRNA S(4)U 4-thiouridine synthase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (423 aa)    
Predicted Functional Partners:
GAK85264.1
Cysteine desulfurase IscS subfamily.
  
 0.972
GAK85265.1
Cysteine desulfurase IscS subfamily.
  
 0.972
rplK
LSU ribosomal protein L11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.905
rsmF
Ribosomal RNA small subunit methyltransferase F; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
  
    0.890
GAK87140.1
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.883
ybeY
Metal-dependent hydrolase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
 
   0.882
GAK82738.1
Hypothetical metal-binding enzyme YcbL homolog.
  
 0.876
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
 0.876
GAK86359.1
AttM/AiiB family protein.
  
 0.876
rplU
LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.875
Your Current Organism:
Vibrio ponticus
NCBI taxonomy Id: 265668
Other names: CCUG 50742, CECT 5869, DSM 16217, V. ponticus, Vibrio ponticus Macian et al. 2005, Vibrio sp. JCM 19238, strain 369
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