node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDD12126.1 | SDD59571.1 | SAMN04488509_101319 | SAMN04488509_10469 | Ribosome-associated protein; Belongs to the UPF0307 family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.893 |
SDD12126.1 | obg | SAMN04488509_101319 | SAMN04488509_101108 | Ribosome-associated protein; Belongs to the UPF0307 family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.828 |
SDD12126.1 | rplC | SAMN04488509_101319 | SAMN04488509_1112 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.848 |
SDD12126.1 | rplO | SAMN04488509_101319 | SAMN04488509_11121 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.827 |
SDD12126.1 | rplQ | SAMN04488509_101319 | SAMN04488509_11128 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L17P. | 0.827 |
SDD12126.1 | rplU | SAMN04488509_101319 | SAMN04488509_101106 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.830 |
SDD12126.1 | rsfS | SAMN04488509_101319 | SAMN04488509_101416 | Ribosome-associated protein; Belongs to the UPF0307 family. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.835 |
SDD59571.1 | SDD12126.1 | SAMN04488509_10469 | SAMN04488509_101319 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome-associated protein; Belongs to the UPF0307 family. | 0.893 |
SDD59571.1 | mnmE | SAMN04488509_10469 | SAMN04488509_10517 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.926 |
SDD59571.1 | obg | SAMN04488509_10469 | SAMN04488509_101108 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.949 |
SDD59571.1 | rlmB | SAMN04488509_10469 | SAMN04488509_102436 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.905 |
SDD59571.1 | rplC | SAMN04488509_10469 | SAMN04488509_1112 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.913 |
SDD59571.1 | rplO | SAMN04488509_10469 | SAMN04488509_11121 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.905 |
SDD59571.1 | rplQ | SAMN04488509_10469 | SAMN04488509_11128 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L17P. | 0.893 |
SDD59571.1 | rplU | SAMN04488509_10469 | SAMN04488509_101106 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.893 |
SDD59571.1 | rsfS | SAMN04488509_10469 | SAMN04488509_101416 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.912 |
SDD59571.1 | truD | SAMN04488509_10469 | SAMN04488509_10884 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA pseudouridine13 synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.895 |
mnmE | SDD59571.1 | SAMN04488509_10517 | SAMN04488509_10469 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.926 |
mnmE | obg | SAMN04488509_10517 | SAMN04488509_101108 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.558 |
mnmE | rlmB | SAMN04488509_10517 | SAMN04488509_102436 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 23S rRNA Gm-2251 2'-O-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.914 |