STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rxyl_0091PFAM: protein of unknown function DUF815; SMART: ATPase; KEGG: mta:Moth_2317 protein of unknown function DUF815. (430 aa)    
Predicted Functional Partners:
Rxyl_0089
PFAM: ABC transporter related; SMART: ATPase; KEGG: tma:TM1028 putative ABC-2 type transport system ATP-binding protein.
  
    0.670
Rxyl_0090
PFAM: ABC-2 type transporter; KEGG: bld:BLi00348 putative permease; RBL02584.
       0.658
Rxyl_0088
PFAM: regulatory protein, MarR; KEGG: ttj:TTHA0953 hypothetical protein.
       0.563
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.526
Rxyl_0725
PFAM: amino acid-binding ACT Prephenate dehydrogenase; KEGG: dra:DR1122 prephenate dehydrogenase.
 
     0.487
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
     0.438
Your Current Organism:
Rubrobacter xylanophilus
NCBI taxonomy Id: 266117
Other names: R. xylanophilus DSM 9941, Rubrobacter xylanophilus DSM 9941, Rubrobacter xylanophilus str. DSM 9941, Rubrobacter xylanophilus strain DSM 9941
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.