STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
rbsKPfkB; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (301 aa)    
Predicted Functional Partners:
rbsD1
RbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
 
 0.960
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 0.947
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
 0.942
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.923
Rxyl_0049
PFAM: Transketolase-like Transketolase, central region; KEGG: ana:all4052 transketolase.
  
 0.922
rbsK-2
PfkB; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
 
0.917
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
   
 
 0.902
Rxyl_0948
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: tte:TTE0206 Periplasmic sugar-binding proteins.
 
  
 0.871
Rxyl_0945
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI periplasmic binding protein/LacI transcriptional regulator; KEGG: sma:SAV5320 putative LacI-family transcriptional regulator.
  
 0.832
rbsD2
RbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
 
 0.831
Your Current Organism:
Rubrobacter xylanophilus
NCBI taxonomy Id: 266117
Other names: R. xylanophilus DSM 9941, Rubrobacter xylanophilus DSM 9941, Rubrobacter xylanophilus str. DSM 9941, Rubrobacter xylanophilus strain DSM 9941
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