node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rmet_3554 | aceF | Rmet_3554 | Rmet_1197 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.850 |
Rmet_3554 | gcvH | Rmet_3554 | Rmet_3481 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.723 |
Rmet_3554 | gcvP | Rmet_3554 | Rmet_3482 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.556 |
Rmet_3554 | lipA | Rmet_3554 | Rmet_0061 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.549 |
Rmet_3554 | lipB | Rmet_3554 | Rmet_0060 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.449 |
Rmet_3554 | lpdA | Rmet_3554 | Rmet_1199 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Dihydrolipoamide dehydrogenase. | 0.785 |
Rmet_3554 | sucB | Rmet_3554 | Rmet_2049 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Dihydrolipoamide succinyltransferase (E2 component); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.854 |
aceF | Rmet_3554 | Rmet_1197 | Rmet_3554 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.850 |
aceF | gcvH | Rmet_1197 | Rmet_3481 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.712 |
aceF | gcvP | Rmet_1197 | Rmet_3482 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.564 |
aceF | lipA | Rmet_1197 | Rmet_0061 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.569 |
aceF | lipB | Rmet_1197 | Rmet_0060 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.566 |
aceF | lpdA | Rmet_1197 | Rmet_1199 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.989 |
aceF | odhL | Rmet_1197 | Rmet_2048 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase (E3 component). | 0.992 |
dmeF | lipA | Rmet_0198 | Rmet_0061 | Co/Zn/Cd efflux system component. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.670 |
gcvH | Rmet_3554 | Rmet_3481 | Rmet_3554 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.723 |
gcvH | aceF | Rmet_3481 | Rmet_1197 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.712 |
gcvH | gcvP | Rmet_3481 | Rmet_3482 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | lipA | Rmet_3481 | Rmet_0061 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.898 |
gcvH | lipB | Rmet_3481 | Rmet_0060 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.865 |