STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mhpD22-Oxopent-4-enoate hydratase. (346 aa)    
Predicted Functional Partners:
Rmet_0279
Fumarylpyruvate hydrolase; Probable 2-keto-4-pentenoate hydratase / 2-oxohepta-3-ene-1,7-dioic acid hydratase (Catechol pathway) oxidoreductase protein.
     
  0.900
sdhA
Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.829
maiA
Maleylacetoacetate isomerase.
 
  
 0.818
sdhB
Succinate dehydrogenase, FeS subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.810
sdhD
Succinate dehydrogenase, membrane subunit, binds cytochrome b556.
   
 
  0.806
sdhC
Succinate dehydrogenase, membrane subunit, binds cytochrome b556.
  
 
  0.805
fumA
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
  0.804
phhA
Phenylalanine-4-hydroxylase (PAH) (Phe-4- monooxygenase).
 
  
 0.707
Rmet_0082
Transcriptional regulator, IclR-family.
       0.577
Rmet_0083
Conserved hypothetical protein.
       0.488
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.