STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gntXPutative amidophosphoribosyltransferase. (279 aa)    
Predicted Functional Partners:
Rmet_3567
DNA processing protein (DprA/Smf type).
 
 
 0.895
Rmet_0237
Probable Mg chelatase-related protein.
 
  
 0.839
Rmet_1043
DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.781
radC-2
DNA binding protein, possibly associated to lesions; Belongs to the UPF0758 family.
 
    0.778
Rmet_3430
Conserved hypothetical protein; predicted endonuclease distantly to archaeal holliday junction resolvase; Belongs to the UPF0102 family.
 
    0.694
yibK
Putative rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
       0.658
tyrA
Prephenate dehydrogenase.
   
  
 0.644
bioC
Putative methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
  
 0.631
Rmet_0591
Putative signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
  
 0.609
apt
Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.606
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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