Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rmet_0366Conserved hypothetical protein. (192 aa)    
Predicted Functional Partners:
Rmet_0367
Putative Fe-S oxidoreductase FAD/FMN-containing dehydrogenase oxidoreductase protein.
       0.538
coxL
Putative carbon-monoxide dehydrogenase, large subunt.
  
    0.485
Rmet_0368
Histidine triad (HIT) protein.
 
     0.484
coxS
Putative carbon monoxide dehydrogenase, 2Fe-2S iron-sulfur small subunit.
  
    0.482
coxM
Putative carbon-monoxide dehydrogenase (acceptor).
  
    0.456
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
Server load: low (18%) [HD]