STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
puuCgamma-Glu-gamma-aminobutyraldehyde dehydrogenase, NAD(P)H-dependent; Belongs to the aldehyde dehydrogenase family. (478 aa)    
Predicted Functional Partners:
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.933
Rmet_1061
acyl-CoA synthetase.
  
 0.932
puuE
GABA aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.930
Rmet_3467
Putative bifunctional P-450:NADPH-P450 reductase 2 (Includes: Cytochrome P450 102; NADPH--cytochrome P450 reductase).
   
 0.926
gadB
Glutamate decarboxylase B, PLP-dependent; Belongs to the group II decarboxylase family.
  
 0.925
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.924
ackA2
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.922
Rmet_0545
Alcohol dehydrogenase, zinc-containing.
 
 0.917
Rmet_1600
Conserved hypothetical protein.
   
 
 0.915
Rmet_1937
Amidase; Belongs to the amidase family.
 
 
 0.914
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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