| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rmet_0881 | ygfU | Rmet_0881 | Rmet_0883 | Conserved hypothetical protein. | Transporter. | 0.864 |
| carA | carB | Rmet_2195 | Rmet_2193 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
| carA | purL | Rmet_2195 | Rmet_1870 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.958 |
| carA | pyrB | Rmet_2195 | Rmet_2740 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrD | Rmet_2195 | Rmet_1213 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.964 |
| carA | pyrE | Rmet_2195 | Rmet_0150 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.943 |
| carA | pyrF | Rmet_2195 | Rmet_3050 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.950 |
| carA | pyrR | Rmet_2195 | Rmet_2741 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Bifunctional protein: pyrimidine operon regulatory protein/uracil phosphoribosyltransferase (UPRTase). | 0.836 |
| carA | pyrX | Rmet_2195 | Rmet_2739 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Dihydroorotase (DHOase). | 0.983 |
| carA | ygfU | Rmet_2195 | Rmet_0883 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | Transporter. | 0.792 |
| carB | carA | Rmet_2193 | Rmet_2195 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | 0.999 |
| carB | purL | Rmet_2193 | Rmet_1870 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.571 |
| carB | pyrB | Rmet_2193 | Rmet_2740 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrD | Rmet_2193 | Rmet_1213 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.967 |
| carB | pyrE | Rmet_2193 | Rmet_0150 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.954 |
| carB | pyrF | Rmet_2193 | Rmet_3050 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.950 |
| carB | pyrR | Rmet_2193 | Rmet_2741 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Bifunctional protein: pyrimidine operon regulatory protein/uracil phosphoribosyltransferase (UPRTase). | 0.923 |
| carB | pyrX | Rmet_2193 | Rmet_2739 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Dihydroorotase (DHOase). | 0.983 |
| carB | ygfU | Rmet_2193 | Rmet_0883 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Transporter. | 0.787 |
| purL | carA | Rmet_1870 | Rmet_2195 | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Belongs to the CarA family. | 0.958 |