STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rmet_0885Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (117 aa)    
Predicted Functional Partners:
Rmet_0881
Conserved hypothetical protein.
 
 0.998
Rmet_0886
Putative membrane protein.
 
  
 0.940
Rmet_0882
Predicted xylanase/chitin deacetylase.
 
    0.873
xdhB
Xanthine dehydrogenase, subunit B.
 
  
 0.771
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
  
 0.769
xdhC
Xanthine dehydrogenase, maturation factor.
 
    0.727
xdhA
Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A.
 
    0.697
Rmet_0884
Transcriptional regulator, GntR-family.
 
    0.629
yedZ
Putative heme-molybdoenzyme heme-containing subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reducta [...]
   
    0.569
ygfU
Transporter.
 
  
 0.502
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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