STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ureEUrea amidohydrolase (urease) accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (206 aa)    
Predicted Functional Partners:
ureF
Urea amidohydrolase (urease) accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 0.998
ureB
Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
 
  
 0.996
ureC
Urea amidohydrolase (urease) alpha subunit.
 
  
 0.996
ureG
Urea amidohydrolase (urease) regulatory and maturation protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.985
ureA
Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.
 
  
 0.984
ureD
Urea amidohydrolase (urease) accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.958
ureJ
Urea amidohydrolase (urease) accessory protein UreJ.
 
  
 0.878
hypB2
GTP hydrolase involved in nickel liganding into hydrogenases.
  
 
 0.732
hypB1
HypB1 GTP hydrolase involved in nickel liganding into hydrogenases (CMGI-2).
  
 
 0.731
Rmet_0954
Putative branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.710
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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