STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureFUrea amidohydrolase (urease) accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (230 aa)    
Predicted Functional Partners:
ureE
Urea amidohydrolase (urease) accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
  
 0.998
ureC
Urea amidohydrolase (urease) alpha subunit.
 
 
 0.997
ureD
Urea amidohydrolase (urease) accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.995
ureG
Urea amidohydrolase (urease) regulatory and maturation protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.993
ureB
Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
 
 
 0.985
ureA
Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.
 
 
 0.984
hypB2
GTP hydrolase involved in nickel liganding into hydrogenases.
  
 
 0.831
hypB1
HypB1 GTP hydrolase involved in nickel liganding into hydrogenases (CMGI-2).
  
 
 0.830
ureJ
Urea amidohydrolase (urease) accessory protein UreJ.
 
  
 0.773
livG9
ABC-type transporter, ATP-binding protein (livG-like).
 
   
 0.686
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.