STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrBTyrosine aminotransferase, tyrosine-repressible, PLP-dependent. (398 aa)    
Predicted Functional Partners:
phhA
Phenylalanine-4-hydroxylase (PAH) (Phe-4- monooxygenase).
  
 
 0.953
pheA
Prephenate dehydratase, Chorismate mutase.
  
 
 0.947
tyrA
Prephenate dehydrogenase.
  
 
 0.922
hisC
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.916
hisC1
Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.915
metK
Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.909
ybiC
Hydroxyacid dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family.
   
 
 0.909
dat
D-amino-acid transaminase, aminotransferase class IV (D-alanine transaminase).
     
 0.909
bhmT
Homocysteine S-methyltransferase.
     
 0.907
dadA2
D-amino-acid dehydrogenase 2 small subunit; Oxidative deamination of D-amino acids.
   
 
 0.905
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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