Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
hpcHHpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (251 aa)    
Predicted Functional Partners:
Rmet_1115
Conserved hypothetical protein (IucA/IucC-like).
 
    0.919
ocd
Ornithine cyclodeaminase (OCD).
 
    0.905
cysK
Cysteine synthase; Catalyzes the synthesis of N-((2S)-2-amino-2-carboxyethyl)-L- glutamate (ACEGA) from O-phospho-L-serine and L-glutamate.
  
    0.856
Rmet_1114
Permeases of the major facilitator superfamily.
 
    0.838
Rmet_1113
Putative siderophore synthetase component protein.
 
    0.830
Rmet_1112
Putative siderophore biosynthesis protein.
 
    0.823
lysA
Diaminopimelate decarboxylase (DAP decarboxylase); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
    0.697
gudD
(D)-glucarate dehydratase 1.
 
 
 0.695
garR
Tartronate semialdehyde reductase.
  
 
 0.604
garR-2
2-hydroxy-3-oxopropionate reductase (Tartronate semialdehyde reductase).
  
 
 0.604
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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