STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rmet_1174Periplasmic sensor signal transduction histidine kinase. (504 aa)    
Predicted Functional Partners:
Rmet_1173
Two component transcriptional regulator, winged helix family; Protein-methionine-S-oxide reductase.
 
 
 0.962
kdpC
Potassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.651
kdpB
Potassium translocating ATPase, subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
  
  
 0.632
pilH
Type IV pilus response regulator PilH.
 
 
 0.623
hmzR
Two component heavy metal response transcriptional DNA binding regulator, winged helix family precursor.
 
 0.616
evgS
Hybrid sensory histidine kinase in two-component regulatory system.
 
0.602
agrR
DNA-binding response regulator in two-component regulatory system with AgrS.
 
 0.587
ompR
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 0.586
creB
DNA-binding response regulator in two-component regulatory system with CreC.
 
 
 0.579
Rmet_1627
DNA-binding response regulator in two-component regulatory system.
 
 0.573
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.