STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypC1HypC1 hydrogenase 2 accessory protein (CMGI-2). (75 aa)    
Predicted Functional Partners:
hypD1
Protein required for maturation of hydrogenases (CMGI-2); Belongs to the HypD family.
 
 
 0.982
hypE1
Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein (CMGI-2).
 
 
 0.976
hypF1
HypF1 hydrogenase maturation protein (CMGI-2).
 
 
 0.957
hypB1
HypB1 GTP hydrolase involved in nickel liganding into hydrogenases (CMGI-2).
 
  
 0.951
hypD2
Protein required for maturation of hydrogenases; Belongs to the HypD family.
 
 
 0.922
hypE2
Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein.
 
 
 0.897
hypA1
HypA1 Hydrogenase nickel incorporation protein hypA (CMGI-2); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.848
hypB2
GTP hydrolase involved in nickel liganding into hydrogenases.
 
  
 0.823
hypF2
Carbamoyl phosphate phosphatase and maturation protein for (NiFe) hydrogenases; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.819
hoxV
HoxV Hydrogenase expression/formation protein hoxV (CMGI-2).
  
 
 0.764
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.