STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypA1HypA1 Hydrogenase nickel incorporation protein hypA (CMGI-2); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (115 aa)    
Predicted Functional Partners:
hypB1
HypB1 GTP hydrolase involved in nickel liganding into hydrogenases (CMGI-2).
 
 
 0.961
hoxV
HoxV Hydrogenase expression/formation protein hoxV (CMGI-2).
 
 
 0.937
hoxL
HoxL hydrogenase expression/formation protein hoxL (belongs to CMGI-2).
 
  
 0.928
hoxT
HoxT putative hydrogenase expression/formation protein (CMGI-2).
 
  
 0.923
hoxQ
HoxQ protein involved in nickel incorporation into hydrogenase-1 proteins(belongs to CMGI-2).
 
  
 0.921
hoxG
HoxG hydrogenase 1, large subunit Uptake hydrogenase large subunit (Hydrogenlyase) (Membrane-bound hydrogenase large subunit) (belongs to CMGI-2).
 
 
 0.916
hoxM
HoxM protein involved in processing of HyaA and HyaB proteins Hydrolase; Nickel Metalloprotease; (belongs to CMGI-2)Protease Absolutely required for hydrogenase activity.
 
  
 0.904
hoxO
HoxO Hydrogenase expression/formation protein hoxO (belongs to CMGI-2); Belongs to the HupG/HyaE family.
 
  
 0.897
hypE1
Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein (CMGI-2).
 
  
 0.889
hypD1
Protein required for maturation of hydrogenases (CMGI-2); Belongs to the HypD family.
 
  
 0.888
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.