STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmpC2-hydroxymuconic semialdehyde dehydrogenase (HMSD)(protein belongs to CMGI-2). (503 aa)    
Predicted Functional Partners:
dmpB
Metapyrocatechase (MPC) (CatO2ase) (Catechol 2,3- dioxygenase) (C23O) (protein belongs to CMGI-2).
 
 
 0.973
nahJ
4-oxalocrotonate tautomerase family enzyme (protein belongs to CMGI-2).
 
  
 0.970
Rmet_3080
Putative 4-oxalocrotonate tautomerase protein.
  
 
 0.931
Rmet_0808
4-oxalocrotonate tautomerase.
    
 0.930
Rmet_1306
2-hydroxymuconic semialdehyde hydrolase (HMSH) - alpha/beta hydrolase superfamily (belongs to CMGI-2).
  
 
 0.928
xylJ
2-hydroxypent-2,4-dienoate hydratase (protein belongs to CMGI-2).
 
  
 0.844
dmpH
4-oxalocrotonate decarboxylase (protein belongs to CMGI-2).
 
  
 0.777
mhpF
Acetaldehyde-CoA dehydrogenase II, NAD-binding (protein belongs to CMGI-2); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.660
Rmet_1325
Ferredoxin (protein belongs to CMGI-2).
 
  
 0.657
bphI
4-hydroxy-2-oxovalerate aldolase 1; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.651
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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