STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phaAAcetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)    
Predicted Functional Partners:
Rmet_0386
Putative 3-hydroxyacyl-coa dehydrogenase oxidoreductase protein.
 
 0.997
fadB
3-hydroxyacyl-CoA dehydrogenase; Fused 3-hydroxybutyryl-CoA epimerase and delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase and enoyl-CoA hydratase; 3-hydroxyacyl-CoA dehydrogenase.
 0.997
phaB
Acetoacetyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.989
hbdA
3-hydroxybutyryl-CoA dehydrogenase.
 0.978
paaH
3-hydroxybutyryl-CoA dehydrogenase.
 0.968
phaB2
Conserved hypothetical protein (partial)(gene belongs to CMGI-2).
 
 0.943
Rmet_0108
acyl-CoA dehydrogenase, short-chain specific.
  
 0.937
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.930
acsA
Acetoacetyl-CoA synthetase.
  
 
 0.929
Rmet_1061
acyl-CoA synthetase.
  
 
 0.928
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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