STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rmet_1380Signal transduction histidine kinase. (390 aa)    
Predicted Functional Partners:
lytT
Response regulator containing a LytTR DNA-binding domain.
 
 
 0.973
ytfP
Conserved hypothetical protein.
  
    0.531
rraA
Ribonuclease E (RNase E) inhibitor protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
  
    0.518
Rmet_2335
Putative exported protein.
  
 
 0.516
cysB
DNA-binding transcriptional activator of cysteine biosynthesis; Belongs to the LysR transcriptional regulatory family.
 
    0.515
Rmet_0591
Putative signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
   
 0.489
Rmet_1905
Transcriptional regulator, LacI-family.
  
   
 0.474
Rmet_1740
Putative membrane protein.
  
  
 0.452
cysA
Sulfate/thiosulfate transporter subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
    0.438
cysW
Sulfate/thiosulfate transporter subunit; membrane component of ABC superfamily.
  
    0.431
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.