STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbbA2Fructose-bisphosphate aldolase (Fba); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa)    
Predicted Functional Partners:
cbbG1
Glyceraldehyde-3-phosphate dehydrogenase A (GAPDH-A); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.983
cbbJ1
Triosephosphate isomerase (CbbJ); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.981
cbbT1
Transketolase 1, thiamin-binding protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.973
pgk1
Phosphoglycerate kinase (Pgk); Belongs to the phosphoglycerate kinase family.
  
 0.967
pykA2
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.966
cbbF2
Fructose-1,6-bisphosphatase I.
  
 
 0.959
cbbG2
Glyceraldehyde-3-phosphate dehydrogenase A (CbbG); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.958
cbbJ2
Triosephosphate isomerase (cbbJ); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.952
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.937
cbbT2
Transketolase 1, thiamin-binding protein; Belongs to the transketolase family.
  
 
 0.934
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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