STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptpS6-Pyruvoyl tetrahydrobiopterin synthase protein. (158 aa)    
Predicted Functional Partners:
queE
Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.996
folE2-1
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
 
 0.912
folE2-2
Putative GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
 
 0.912
ntpA
dATP pyrophosphohydrolase protein.
  
 
  0.902
Rmet_1101
Putative 6-pyruvoyl-tetrahydropterin (PTP)synthase.
   
 
  0.900
phoD
Phosphodiesterase/alkaline phosphatase D.
     
  0.900
Rmet_2613
Alkaline phosphatase.
   
 
  0.900
queC
Queuosine biosynthesis protein queC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.900
ldcA
L,D-carboxypeptidase A.
  
    0.749
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase (NADPH- dependent nitrile oxidoreductase); Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.745
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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