STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agrACation/multidrug efflux pump, RND family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1065 aa)    
Predicted Functional Partners:
agrB
RND efflux pump, membrane fusion protein, CzcB subfamily; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.968
agrC
RND efflux system, outer membrane lipoprotein, NodT.
 
 0.854
mdtA
Multidrug efflux system, subunit A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.774
mdtA-2
Multidrug resistance protein mdtA precursor (Multidrug transporter mdtA); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.761
Rmet_3581
Putative multidrug RND transporter, membrane fusion protein (AcrA-MtdA-HylD family); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.635
agrS
Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.
  
 
 0.552
agrR
DNA-binding response regulator in two-component regulatory system with AgrS.
     
 0.511
acrA
Cation/multidrug efflux system, mebrane-fusion component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.492
Rmet_1943
Cation/multidrug efflux system, mebrane-fusion component (modular protein) (RND family); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.457
Rmet_0598
Ser/Thr protein phosphatase family protein.
  
     0.441
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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