STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfaCLipopolysaccharide heptosyltransferase I. (340 aa)    
Predicted Functional Partners:
rfaF
ADP-heptose:LPS heptosyltransferase II.
 
 0.990
kdtA
3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 
 0.956
Rmet_2712
Putative cell surface polysaccharide polymerase/ligase.
  
 
 0.917
rfaC-2
ADP-heptose:LPS heptosyl transferase I.
  
 
 
0.917
rfaE
Fused heptose 7-phosphate kinase; heptose 1-phosphate adenyltransferase.
 
  
 0.862
hldC
D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
 
  
 0.858
gmhB
D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.
 
  
 0.716
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.694
yraO
DnaA initiator-associating factor for replication initiation; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
 
   
 0.656
fdx
Ferredoxin (4Fe-4S cluster-containing protein) (fdx-like).
  
   0.624
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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