STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topB2DNA topoisomerase III. (676 aa)    
Predicted Functional Partners:
ssb2
Single-stranded DNA binding protein.
 
 
 0.994
recQ
ATP-dependent DNA helicase.
 
 0.986
ssb1
Single-stranded DNA-binding protein (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.965
gltB
Glutamate synthase, large subunit.
  
  
 0.963
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.936
Rmet_2295
Conserved hypothetical protein.
 
  
 0.850
Rmet_2292
Putative regulator.
 
  
 0.821
ppd
Phosphonopyruvate decarboxylase.
  
    0.812
Rmet_2330
Putative plasmid-related DNA/RNA helicase.
 
 
 0.797
Rmet_2353
Type IV secretory pathway, VirB4 components.
 
  
 0.794
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.