| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rmet_0102 | Rmet_1823 | Rmet_0102 | Rmet_1823 | Transcriptional regulator, MerR-family. | Conserved hypothetical protein. | 0.597 |
| Rmet_0102 | dnaJ | Rmet_0102 | Rmet_2921 | Transcriptional regulator, MerR-family. | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.538 |
| Rmet_0102 | evgS | Rmet_0102 | Rmet_2154 | Transcriptional regulator, MerR-family. | Hybrid sensory histidine kinase in two-component regulatory system. | 0.470 |
| Rmet_0102 | pbrR2 | Rmet_0102 | Rmet_2302 | Transcriptional regulator, MerR-family. | Transcriptional regulator, MerR-family. | 0.753 |
| Rmet_0102 | rpoB | Rmet_0102 | Rmet_3334 | Transcriptional regulator, MerR-family. | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.427 |
| Rmet_0942 | pbrR2 | Rmet_0942 | Rmet_2302 | Putative ADP-ribose pyrophosphatase. | Transcriptional regulator, MerR-family. | 0.461 |
| Rmet_1823 | Rmet_0102 | Rmet_1823 | Rmet_0102 | Conserved hypothetical protein. | Transcriptional regulator, MerR-family. | 0.597 |
| Rmet_1823 | evgS | Rmet_1823 | Rmet_2154 | Conserved hypothetical protein. | Hybrid sensory histidine kinase in two-component regulatory system. | 0.534 |
| Rmet_1823 | pbrR2 | Rmet_1823 | Rmet_2302 | Conserved hypothetical protein. | Transcriptional regulator, MerR-family. | 0.538 |
| cadA | pbrC2 | Rmet_2303 | Rmet_2304 | Lead/cadmium-transporting ATPase (cation efflux ATPase). | Prolipoprotein signal peptidase (signal peptidase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.873 |
| cadA | pbrR2 | Rmet_2303 | Rmet_2302 | Lead/cadmium-transporting ATPase (cation efflux ATPase). | Transcriptional regulator, MerR-family. | 0.884 |
| dnaJ | Rmet_0102 | Rmet_2921 | Rmet_0102 | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Transcriptional regulator, MerR-family. | 0.538 |
| dnaJ | evgS | Rmet_2921 | Rmet_2154 | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Hybrid sensory histidine kinase in two-component regulatory system. | 0.536 |
| dnaJ | pbrR2 | Rmet_2921 | Rmet_2302 | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Transcriptional regulator, MerR-family. | 0.538 |
| dnaJ | rpoD1 | Rmet_2921 | Rmet_2606 | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | RNA polymerase sigma D factor (housekeeping sigma factor); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.585 |
| evgS | Rmet_0102 | Rmet_2154 | Rmet_0102 | Hybrid sensory histidine kinase in two-component regulatory system. | Transcriptional regulator, MerR-family. | 0.470 |
| evgS | Rmet_1823 | Rmet_2154 | Rmet_1823 | Hybrid sensory histidine kinase in two-component regulatory system. | Conserved hypothetical protein. | 0.534 |
| evgS | dnaJ | Rmet_2154 | Rmet_2921 | Hybrid sensory histidine kinase in two-component regulatory system. | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.536 |
| evgS | merA' | Rmet_2154 | Rmet_2315 | Hybrid sensory histidine kinase in two-component regulatory system. | Mercuric reductase. | 0.412 |
| evgS | pbrR2 | Rmet_2154 | Rmet_2302 | Hybrid sensory histidine kinase in two-component regulatory system. | Transcriptional regulator, MerR-family. | 0.471 |