STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoERNA polymerase sigma 24 (sigma E) factor; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)    
Predicted Functional Partners:
rseA
Anti-sigma factor, negative regulator of sigma24 activity.
  
 
 0.871
rseB
Anti-sigma factor, negative regulator of sigma24 activity.
 
 
 0.843
rpoL
RNA polymerase sigma L factor (ECF:FecI-like); Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.775
rpoI
RNA polymerase sigma I (sigma 19) factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.718
rpoR
RNA polymerase sigma R factor (ECF); Belongs to the sigma-70 factor family. ECF subfamily.
   
  
 0.650
sspB
ClpXP protease specificity-enhancing factor.
  
  
 0.582
rpoA
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.505
Rmet_0596
Putative transmembrane transcriptional regulator (Anti-sigma factor).
  
 
 0.503
Rmet_3279
Putative transmembrane transcriptional regulator (anti-sigma factor).
  
 
 0.503
rpoC
RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.498
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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